Having successfully defeated the Moja Corps, the LocoRoco settle back in their peaceful life. However, Bon Mucho, the Moja Boss, is not willing to accept defeat, so he devises a terrible song that can suck the life force out of living things, as a new attack on the LocoRoco. Armed with this fearsome song, the Moja boarded their meteorite and set off once more on a mission to conquer the LocoRoco planet. Back there, the LocoRoco finds the new MuiMui house, but right after, the meteor comes crashing down onto a Nyokki, and the Mojas start attacking again (sucking the life force out of living things, and as usual, eating LocoRoco). The LocoRoco then set off on an ever more epic journey to restore the life force into living things and to defeat the Moja Corps.